Antipyretic rectal suppositories for fever for adults. Names, prices

The effectiveness of antipyretic suppositories for adults

Suppositories for fever (adults and children are prescribed different medications) differ in the following principle of action:

• Penetration of the active component of the drug through the intestinal mucosa (in the ampoule of the rectum).
• Its absorption by tissues.
• The medication enters the lower and middle hemorrhoidal veins, and then into the general bloodstream.
• The effect of the main component on the thermoregulation center in the hypothalamus.
• Reduced heat generation and heat transfer through the skin.
• Decreased body temperature.

The advantages of treatment using suppositories are the following factors:

• the possibility of treating patients with vomiting, swallowing disorders, gastrointestinal diseases and in unconscious patients;
• ease of use at home;
• painless route of administration (compared to injection);
• lack of active metabolism in the liver, influence on the gastrointestinal mucosa;
• fewer side effects;
• Possibility of use in pediatric practice, in elderly and mentally ill patients.

Pros and cons of using suppositories

Babies are called babies from 1 month to a year. Fever in children of this age is usually brought down with drugs in the form of syrups or suppositories. The latter form is more preferable.

The use of temperature control candles for infants has the following advantages:

• no stress on the stomach. Preparations of this form do not cause side effects from the digestive tract;
• performance. Suppositories are introduced into the intestine, where they begin to be absorbed into the general bloodstream. Since the medicine bypasses the stomach, its clinical effect is achieved faster;
• long-term action;
• Ease of use;
• efficiency. In addition to fever, some suppositories also relieve pain. They are suitable for reducing fever after vaccination and during teething.

Syrups are rarely used for babies. In infants, due to fever, nausea, vomiting and allergies to additional components of the pharmaceutical product in this form of release may occur. Despite the presence of a number of advantages, rectal antipyretics have certain disadvantages, which are useful for parents to know about.

Disadvantages of suppositories for high fever for babies:

• injection of the drug into the intestine causes discomfort in the baby. He may begin to be capricious and cry. Many children actively resist such a procedure;
• To relieve fever, pharmaceutical companies produce many different suppositories. This complicates the choice of drug;
• if a child has intestinal pathologies, then using suppositories to relieve fever is not recommended;
• Most suppositories can be used from the age of three months.

Antipyretic suppositories are recommended to be placed after a cleansing enema or natural bowel movement. Otherwise, they may not have the desired antipyretic effect.

Additional properties

In addition to reducing temperature, suppositories can have the following additional types of effects:

• anesthetic;
• anti-inflammatory;
• membrane stabilizing;

• antispasmodic;
• immunomodulatory.

Types of suppositories with antipyretic effect

Suppositories with antipyretic effect are classified according to the following criteria:

• By form:

1. cylindrical;
2. conical;
3. cigar-shaped.

• According to the origin of the candle base:

1. natural (cocoa butter, as well as its analogues);
2. products of processing of natural substances (gelatin, glycerin, vitepsol, fats);
3. artificial (obtained synthetically).

• According to the main antipyretic component:

1. based on paracetamol;
2. based on metamizole sodium;
3. based on indomethacin and other antipyretic substances.

Precautionary measures

Precautionary measures when using antipyretic suppositories are quite simple, but they should not be neglected.

1. Study the instructions for the medicine before using it.
2. Store suppositories in the refrigerator, so the shape and consistency will not be affected.
3. Strictly follow the dosage prescribed by your doctor.
4. Do not take for more than 3-5 days (depending on specialist recommendations).
5. Paracetamol-based products should not be combined with medications with the same active ingredient.
6. It is better to replace antipyretic suppositories for children over 3 years old with syrup or tablets.
7. Introduce fever suppositories for children according to the rules to prevent injury.

At what temperature is the use of suppositories indicated?

Just as for children, doctors recommend lowering body temperature in adults if it exceeds +38...+39°C. However, it is necessary to focus on general well-being. If it worsens significantly when a febrile state occurs, then antipyretics are prescribed.

Patients with neurological, cardiovascular and other severe somatic diseases are also at risk for possible complications from hyperthermia.

Adverse reactions

Side effects that suppositories may cause are described in the table below:

Contraindications

Suppositories for fever are prescribed to adults in the absence of contraindications indicated in the table.

General contraindications are inflammation of the rectal mucosa and recent bleeding from it.

List of rectal suppositories for reducing fever in adults

Temperature suppositories may have various components that have an antipyretic effect. The most widely used suppositories for adults and their brief descriptions are given in the table below.

Viferon

Viferon rectal suppositories for adults are available in 3 dosages - 500 thousand, 1 million and 3 million IU. The drug is not an antipyretic, but an immunomodulator. However, due to its immunostimulating and antiviral effects, it helps reduce the duration of a febrile state by an average of 1.5-2 days.

The main indications for its use are:

• ARVI, influenza;
• herpes (including genital);
• papillomatosis;
• urogenital infections (chlamydia, ureaplasmosis, vaginosis, trichomoniasis, candidiasis, gardnerellosis and others);
• pneumonia (in complex treatment);
• other infectious diseases (cytomegalovirus infection, sepsis, viral hepatitis, enterovirus infection and others).

It is possible to use the drug during pregnancy (from 14 weeks), as well as during breastfeeding. In this case, a dosage of 500 thousand IU is used. The duration of treatment is 5-10 days (longer if necessary). Dosage – 1-2 suppositories per day.

Viburkol

Viburkol refers to homeopathic medicines, which contain the following main components:

• pharmaceutical camomile;
• belladonna;
• bittersweet nightshade;
• large plantain;
• meadow lumbago;
• calcium carbonicum (carbonic and phosphate lime).

The main purpose is to reduce fever and inflammation in acute respiratory diseases, as well as during teething in children. Dosage – up to 6 suppositories per day at temperatures above +38°C, and after normalization – 1 suppository 1-2 times a day to consolidate the effect for 3-4 days.

Cefekon N

Suppositories for fever are rarely prescribed to adults.

Cefekon N contains the following components:

• non-steroidal anti-inflammatory component – ​​naproxen;
• stimulant of the central nervous system, antispasmodic, analeptic (activation of the respiratory and vasomotor centers in the brain) - caffeine;
• antipyretic – salicylamide.

The basis of the suppository is vitepsol - a mixture of solid triglycerides of plant origin.

The drug is not only prescribed to reduce fever, but also as an analgesic for the following conditions:

• damage to peripheral nerves;
• muscle, toothache and headache;
• pain during menstrual bleeding in women;
• inflammation of the sciatic nerve;
• shootings in the back;
• osteochondrosis and other degenerative diseases of the musculoskeletal system.

Dosage – 1 suppository 1-3 times a day.

Genferon

Genferon is an immunomodulator.

It contains not only human interferon, but also additional components:

• benzocaine is a substance that has a local anesthetic effect (blocking the conduction of nerve impulses);
• taurine is a compound that has anti-inflammatory, antioxidant, regenerating (restorative), membrane stabilizing (preventing the development of allergic reactions) effect.

  
  Genferon 500000 candles

The drug has the same indications as Viferon, and is also used in the complex therapy of additional inflammatory diseases of the following localization:

• Cervix;
• Bartholin glands located in the vestibule of the vagina (bartholinitis);
• ovaries and/or fallopian tubes;
• prostate;
• urethra;
• head of the penis.

The dosing principle is the same as that of Viferon.

Analgin

Suppositories for fever in adults called Analgin are available in 2 dosages - 100 mg and 250 mg. The total daily dose should not exceed 1.5 g (single dose - 250-500 mg). The main purpose of the drug is to reduce temperature and reduce pain. The mechanism of action of the active substance, metamizole sodium, is associated with the suppression of prostaglandin production.

With long-term use of this drug, it is necessary to monitor blood parameters, as complications may occur. It is not recommended to use it together with other NSAIDs, as their toxic effects are enhanced. Increases the activity of anticoagulants, glucocorticosteroids and indomethacin, drugs containing acetylsalicylic acid, antibiotics.

Analdim

Analdim suppositories are produced by Monfarm OJSC (Ukraine) in dosages of 100 and 250 mg. In addition to metamizole sodium, they contain diphenhydramine, which has an antihistamine (anti-allergic) and sedative effect, and also enhances the effect of analgin. The dosage is the same as for the previous drug.

The main indications for this drug are:

• inflammatory diseases accompanied by elevated body temperature;
• toothache, muscle pain, headache;
• relief of pain in the postoperative period or as a result of injury;
• renal and hepatic colic.

Panadol

Despite the fact that Panadol suppositories are most often used in pediatric practice, according to the instructions they can also be used in adults. The drug is available in dosages of 125 and 250 mg, and a single dose for adults is 500 mg, that is, 2 suppositories are required. The maximum frequency of use per day should not exceed 4 doses.

Candles are used in the following cases:

• febrile state during infectious and inflammatory diseases;
• headache, toothache, muscle pain;
• neuralgia;
• pain after injuries, burns;
• pain during menstruation.

Long-term use also requires monitoring of the blood condition.

Indomethacin

Indomethacin suppositories have anti-inflammatory, analgesic, and antipyretic effects. They are available in 2 dosages: 50 and 100 mg. Suppositories are administered 1 pc. 1-2 times a day.

The drug is prescribed to reduce temperature in infectious and inflammatory diseases, as well as in the following cases:

• pain in joints, spine, muscles;
• neuralgia;
• pain syndrome during menstrual bleeding in women.

Papaverine

The content of the active component of the same name in Papaverine suppositories is 20 mg.

This drug is not used as an independent antipyretic drug, since the main pharmacological effect is to reduce the tone of the smooth muscles of internal organs and dilate blood vessels, which leads to an increase in blood flow (including in the brain).

It is prescribed in combination with medications that more effectively reduce body temperature. A single dosage is 20-40 mg. Candles can be placed 2-3 times a day (with an interval of 4 hours). In elderly people, the initial dosage should be no more than 10 mg.

Diclofenac

This type of suppository contains 100 mg of diclofenac in each suppository. The main component belongs to the group of NSAIDs and has a moderate antipyretic effect. In addition, it is able to relieve pain and has an anti-inflammatory effect.

In addition to infectious and inflammatory diseases of the ENT organs, suppositories are prescribed in the following cases:

• inflammation of the joints, spine;
• pain syndrome due to damage to the musculoskeletal system;
• neuralgia;
• pain during menstrual bleeding in women;
• inflammatory diseases in the pelvis;
• post-traumatic pain.

The recommended treatment regimen is 1 suppository at night.

Laferobion

Laferobion is a Ukrainian-made analogue of Viferon, which is available in 2 dosages - 150 thousand IU (for children) and 500 thousand IU. Just like previous immunomodulatory agents, it helps to relieve viral infections, having an indirect effect on body temperature.

In addition, it is prescribed in the complex therapy of multiple sclerosis and the following oncological pathologies:

• melanoma (skin tumor developing from pigment cells);
• cancer of internal organs (kidneys, bladder and others);
• breast cancer and other malignant tumors.

When treating ARVI and influenza, the dosage for adults is 1 suppository per day.

Antipyretic drugs (Top 10)

1. Viburkol

Viburkol is an analgesic, antipyretic, antispasmodic, and also has a sedative effect. The product is also used during teething. Allergic reactions and mild diarrhea are possible (1 in 10,000).

Important ! Viburkol is a homeopathic medicine.

Use is allowed only from infancy, that is, after the 1st month of life. Babies up to six months are given 1 dose 2 times a day. For older children, with a temperature above 37.5⁰C, 1 suppository is prescribed 4 times a day, and if it is already above 38⁰C, 1 dose 6 times a day. When the condition has stabilized, take 1 suppository 1-2 times a day at intervals of 12-24 hours over the next 3-4 days.

Cost – 372-414 rubles.

2. Viferon

Viferon is both an antiviral and antipyretic medicine, created on the basis of interferon, effective for acute respiratory viral infections, pneumonia, meningitis, and sepsis. It is given starting from the 1st day of life. Viferon may be used no more than three times in 1 day and no longer than 5 days.

Possible unpleasant consequences include:

• allergy to some components of suppositories. These manifestations go away on their own within 3 days after stopping taking Viferon;
• headache;
• spontaneous bowel movement.

Price – 239-366 rubles.

3. Nurofen

Nurofen is a complex drug that has anti-inflammatory, antipyretic and analgesic effects. The effect is due to the work of the active ingredient – ​​ibuprofen.

Which temperature control candles are best for children?

Nurofen is given 1 suppository every 12 hours. After administration, tachycardia, sometimes dizziness or drowsiness are possible.

Important ! Nurofen is given to babies aged 3 months and older.

You can buy it for 88-110 rubles.

4. Panadol

Panadol is made from paracetamol and works as an antipyretic, antiviral and analgesic.

It can only be prescribed to children over 1 year of age. The dosage is determined based on the need to take 15 mg per 1 kg of patient weight. Panadol is given up to 4 times every 24 hours, but not more than for 3 days.

Unpleasant consequences may include:

• pallor;
• nausea;
• skin manifestations of allergic etymology;
• abdominal pain.

Price – 67-79 rubles.

5. Cefekon D

Cefekon D, due to the fact that the base is paracetamol, demonstrates an analgesic and antipyretic effect. It is prescribed for ARVI and for pain relief, when teeth are being cut, there have been injuries or burns.

The medication is intended for children over 3 months old, but a single use is allowed 1-3 months after vaccinations.

Side effects rarely include abdominal pain. Sometimes nausea and vomiting occur. There are skin allergic reactions, Quincke's edema. Tachycardia and anemia may occur. Parents report drowsiness or, conversely, overexcitement.

Cost - 57-114 rubles

6. Dafalgan

The main active ingredient of Dafalgan is paracetamol. The product is an antipyretic with a pronounced sedative effect. Appointment is possible starting from 3 months of age. In children under 12 years of age, Dafalgan can be used for a maximum of 3 days. It is recommended to maintain an interval between the administration of suppositories of 6-8 hours. The dosage is determined based on the patient's weight.

The use of Dafalgan is contraindicated for:

• liver diseases;
• increased susceptibility to paracetamol.

Price – 240 rubles.

7. Mexalen is an antipyretic that is also an analgesic. The basic substance is paracetamol.

The medicine should not be prescribed if you are allergic to its individual components, if you have impaired liver or kidney function, or if you are younger than 1 month.

Mexalen suppositories are given no more than 3 times a day. The minimum acceptable interval between doses is 4 hours.

Cost – 31-51 rubles.

8. Efferalgan is prescribed to children as an antipyretic and analgesic during acute respiratory viral infections, tonsillitis, and when teeth are being cut. The base compound is paracetamol.

The dosage is determined taking into account the patient's weight. It is allowed to take no more than 4 suppositories per day for a maximum of 3 days as an antipyretic and 5 days as an analgesic.

Contraindications:

• diarrhea;
• bleeding in the rectum;
• less than 3 months old.

Important ! In case of impaired renal function, the regimen for using Efferalgan is determined taking into account creatinine levels.

After use very rarely occur:

• diarrhea;
• pain in the abdomen;
• nausea;
• vomit;
• anemia;
• allergic manifestations;
• irritation in the rectum;
• liver necrosis;
• hepatitis.

Price – 60-118 rubles.

9. Analdim was obtained by combining analgin and diphenhydramine. This is a lytic mixture used for infections, inflammation, when suffering from headaches and toothaches, kidney or liver colic, spasms in muscle tissue, and neuralgia.

The medicine is used as an antipyretic and analgesic. Candles are given a maximum of 1 time per day.

Important ! Analdim suppositories are an emergency response when convulsions, severe headaches, and so on may develop. The maximum effect appears after 1-2 hours and is manifested in a decrease in temperature by 2-3 degrees.

Contraindications:

• age up to 1 year;
• liver and kidney dysfunction;
• deficiency of glucose-6-phosphate dehydrogenase;
• blood diseases;
• bronchial asthma.

Price – 45-100 rubles.

10. Ibuprofen - anti-inflammatory, analgesic and antipyretic. The main component is the substance of the same name.

Children are offered suppositories based on 20-40 mg of Ibuprofen per 1 kg of weight per day. The received dose is divided into several doses.

Restrictions for prescribing Ibuprofen are:

• erosive and ulcerative phenomena of the gastrointestinal tract during periods of exacerbation;
• painful conditions of the optic nerve;
• "aspirin triad";
• hematopoietic dysfunction;
• kidney or liver problems;
• intolerance to ibuprofen.

Price – 81-90 rubles.

Rules of application

When using rectal suppositories, it is recommended to adhere to the following rules:

1. Wash your hands with soap.

   
   Suppositories for the treatment of cervical erosion must be administered correctly.

2. Release the candle from the shell. To facilitate insertion, it can be moistened with cool water.
3. Lie in a comfortable position (on your left side, bending your right leg at the knee, or on your back, bringing your legs to your stomach).
4. Gently push the candle into the anus as deep as possible.
5. Wash your hands again with soap.
6. Stay in a horizontal position for at least 30-40 minutes.

It is also recommended to use medications after defecation to prevent the urge.

Instructions for using baby suppositories based on temperature

The technology for introducing a suppository is somewhat different for children under and after one year of age. In general, it is necessary to reduce the temperature with suppositories if it exceeds the level of 38.5–39 degrees. Sometimes the use of antipyretics is required in other conditions:

• if the child is not yet 2-3 months old, then the temperature should be brought down when the level exceeds 38 degrees;
• when the baby’s condition has deteriorated greatly and he has difficulty withstanding the fever;
• if you have heart or nervous system diseases;
• in case of fever after administration of the vaccine.

Any suppositories for high fever in children are accompanied by instructions for use. The sequence of administering suppositories to infants under 1 year of age includes the following steps:

1. Shortly before the procedure, remove the suppository from the package.
2. To insert the suppository, choose the time after bowel movement.
3. Wash the anal area and wipe dry.
4. Lay the baby on his back, tuck his legs towards his stomach.
5. Carefully insert the suppository into the anus.
6. Let the child lie on his back for a couple of minutes.

At older ages, suppositories are administered according to almost the same instructions, but there are some differences. Before the procedure, you should ask your child to go to the toilet to empty his bowels. Next you need to do the following:

1. Rinse the anus area and wipe dry.
2. For older children, it is more convenient to insert the suppository in the “squatting” position.
3. After the procedure, make sure that the child lies down until the drug begins to take effect. At this time he should not get up and walk around the room.

special instructions

As with systemic agents, rectal antipyretic drugs can be used for no more than 3 days. If the body temperature does not decrease or the patient’s condition worsens, you should consult a doctor.

They can be used as analgesics for no more than 5 days. If itching or discomfort occurs in the rectum, treatment should be stopped. To eliminate these side effects, you can enter 1 tbsp. l. warm sunflower oil as an enema.

When to deal with a high fever

WHO recommends the use of antipyretics when body temperature is above 38.5⁰C. Before this level is reached, it is believed that the body can cope with the disease on its own. You just don’t need to disturb him, because the presence of fever is a sign of the body’s intensive production of interferon, which destroys viruses.

Important! If the temperature is below 38.5⁰C, and the child does not feel well, he is lethargic and capricious, then it is still worth using antipyretics and consulting a doctor.

If the thermometer shows 40-41⁰C, then we can talk about a serious danger, especially when this condition persists for several days. With such heat, convulsions, heart attack, respiratory arrest are possible, sometimes neurological pathologies, cerebral edema, and so on develop. Such conditions are dangerous with a high probability of death.

Prices

Average prices for the drugs described above in pharmacy chains are shown in the table below.

Temperature suppositories help alleviate the condition of patients in a feverish state. They are also often prescribed to adults for pain syndromes of various origins. A special group of suppositories consists of antiviral agents.

It must be taken into account that long-term use of antipyretic drugs increases the risk of side effects. Even if they are used occasionally, it is recommended to alternate drugs with different main components.