Temperature relief for children. Composition, proportions in tablets, injections, how it works

What is a lytic mixture?

Litichka is a combination of injection solutions of several medications at once, which are mixed together in one syringe and then injected intramuscularly into the patient’s body. The lytic mixture is an absolutely safe antipyretic that is used to relieve children of high body temperature.

The classic composition of the lytic mixture is a medicinal triad, including Analgin, Diphenhydramine and Papaverine hydrochloride. Depending on the severity and type of disease that provoked the fever, other medications can be used during the preparation of lithika with strict adherence to their proportions.

How to make lytic formula for a baby

First of all, it is important to discuss, together with the local pediatrician, the chemical composition of the future medicine, for which disease it is allowed, and when it is better to refrain from such a prescription. Medicines are selected to minimize the risk of side effects during therapy. Before making a lytic mixture for children, it would be advisable to find out the proportions and release form of the finished medicine. If these are tablets, there are no problems. In the case of injections, an additional sterile syringe is purchased and the liquid composition is injected intramuscularly.

Pros and cons of fever in children

Lytic mixture is an effective complex of drugs that is used to quickly relieve the main symptoms of an inflammatory disease of infectious etiology. This therapeutic agent has a number of positive and negative aspects.

The main advantages of lytichka are associated with its pharmacological properties, namely:

• all injectable medications included in the lytic mixture are absolutely affordable, with the average price of 1 ampoule of the drug ranging from 15 to 30 rubles. depending on the type of medicine;
• the injection of the therapeutic solution is carried out intramuscularly, which promotes faster absorption of the active components of the injection with their further distribution throughout the body;
• the lytic mixture is well tolerated by children of the younger age group;
• antipyretic complex of drugs allows within 10 minutes. reduce high body temperature, which was in the range of 38-39 degrees Celsius;
• the active components of lytica have a prolonged effect, which ensures that the antipyretic effect is maintained for 6 hours or more;
• the medications included in the lytic mixture not only help to normalize the body’s heat metabolism, but also dilate blood vessels, have an analgesic, mild sedative and anti-inflammatory effect;
• Intramuscular injection of lytic acid does not require deep knowledge in the field of medicine, and in case of emergency, the injection can be performed independently.

Despite the large number of obvious advantages of the lytic mixture, this therapeutic complex has several important disadvantages.

The following are the disadvantages of lithika, which you should also pay special attention to:

• medications included in the intramuscular injection have side effects that may appear after administration of the solution;
• the lytic mixture has medical contraindications for its use;
• Lytichka can cause an attack of acute allergic reaction in adults and children who have individual intolerance to the active components of Analgin, Papaverine, Diphenhydramine, Suprastin, No-shpa;
• an antipyretic mixture of injection solutions is only a means of symptomatic therapy, which will eliminate the signs of the disease for a short period of time, but does not cure the underlying ailment;
• after 6-8 hours from the moment of administration of the lytic, a repeated increase in body temperature, the appearance of chills and a feverish state are possible;
• Improper execution of an intramuscular injection, as well as failure to comply with sterility standards, can lead to infection with the development of a local inflammatory process.

Before using the lytic mixture to normalize the child’s body temperature, you should consult a pediatrician. This will minimize the risk of developing unwanted reactions of the body.

Side effects of triad from temperature

In order not to overdo it with the introduction of the lytic mixture, parents should remember an important rule - only three injections of the mixture with the same composition can be given per day. Otherwise, adults may experience side effects of the mixture, which include the following:

• irritation of the mucous membrane of the digestive tract, which manifests itself as pain in the stomach after taking the mixture in tablet form;
• lethargy, loss of coordination of movements if the mixture was injected.

Lytic mixture for children is a life-saving remedy for many children with fever. However, it must be remembered that the lytic mixture itself only removes the symptom of the disease, but does not treat its cause. Therefore, it is necessary to call a doctor for the child, and it is important to indicate when, what medications and how often were given to the baby.

Indications for use

The fever remedy for children (the composition and proportions of the therapeutic mixture remain unchanged) is indicated for use in the presence of the following symptoms:

• the child is worried about chills, headache, fever caused by a cold, exposure to a bacterial, viral or fungal infection;

• the patient’s body temperature is 38 degrees or higher, which can provoke a disruption in the functioning of the internal organs and systems of the body;
• the child began to have spasms of the lower extremities, which are caused by an imbalance in the body’s thermal balance;
• the use of antipyretics with other active ingredients did not bring a positive result (the temperature remains within the same limits or continues to rise).

The lytic mixture is recommended for use to alleviate the general well-being of patients with ARVI, colds and inflammatory diseases of infectious etiology.

This therapeutic complex is not used to relieve fever, the occurrence of which is associated with the persistence of prolonged pain inside the abdominal cavity. A second lytic injection can be given no earlier than 6 hours later. The duration of use of the mixture of drugs is 3-5 days, but no more than that.

General information about the lytic mixture

Emergency antipyretics or lytic mixture simultaneously relieve pain and eliminate fever. This combination drug quickly improves the condition of patients. A positive effect is achieved within 15-20 minutes. Before using it, an allergy test is usually performed by injecting the product into the patient's lower eyelid. In the absence of negative reactions, the mixture is used for its intended purpose.

The lytic mixture can only be used in isolated cases, but not on an ongoing basis, as it is considered a very strong remedy. This drug is intended mainly for certain groups of people to get rid of prolonged hyperthermia.

The following are especially needed in the lytic mixture at high temperatures (over 38.5°):

• those suffering from chronic vascular and heart diseases;
• aged people;
• children;
• those who have a hangover;
• patients with severe poisoning or vomiting;
• adults and adolescents who refuse to take conventional antipyretics.

A multicomponent lytic remedy for high fever is recommended if:

• Febrile convulsions are observed against the background of high temperature.
• There are symptoms of pale fever:

1. chills;
2. pale skin;
3. strong heartbeat;
4. coldness of the extremities.

• The patient cannot take tablets or syrup.
• There is no effect from conventional antipyretics:

1. candle;
2. tablets;
3. syrups.

Doctors prescribe an emergency multicomponent remedy for fever intramuscularly to those patients whose temperature rises above 38.5°. This mixture is applicable if Nurofen or Paracetamol do not help. But it is sometimes replaced with antipyretic suppositories or syrups.

Another lytic agent is prescribed if:

• the patient refuses to take regular medications for fever;
• the patient is unconscious;
• a person vomits from taking pills orally.

The lytic mixture is sometimes used at not very high temperatures.

This is done for those patients who have:

• mental or neurotic diseases;
• disturbances of consciousness and convulsions;
• deterioration of general condition;
• acquired or congenital heart defects;
• arrhythmia;
• pale skin.

Compound

The table shows the classic composition of the lytic mixture in the form of a triad, which is used to quickly relieve fever, chills, headaches, and a febrile state of the body.

The complex effect of the above-mentioned drugs that are part of the lytichka allows you to quickly normalize body temperature to 38-39 degrees and above, eliminating the risk of developing seizures and complications in the functioning of internal organs.

It should be remembered that in combination with these medications it is necessary to use potent drugs with anti-inflammatory, antibacterial, restorative and antiviral properties. This will minimize the risk of fever recurring.

Composition of the lytic mixture depending on temperature

The lytic mixture, or as it is affectionately called “lytic”, can be used both in tablets and ampoules. Thrifty parents should have the most convenient “kit” for their child, but in some cases, when all the pharmacies are closed and there are only pills, there is no time to hesitate - that means the pills are taken. Ideally, injections are better, since the drug enters the systemic bloodstream faster and does not have a negative effect on the gastric mucosa.

The “golden composition” of the lytic mixture is Analgin and Diphenhydramine. The work of Analgin is an analgesic and antipyretic effect. Together with Diphenhydramine, which enhances the effect of the first substance, the mixture acquires unique properties. Within 10-15 minutes after intramuscular administration, the child will feel much better, the temperature will begin to drop, the adequacy of consciousness will return, etc.

If necessary, Diphenhydramine can be replaced with another drug that is available in the parents' medicine cabinet. This could be Tavegil, Suprastin or Fenistil, which also enhance the activity of the main savior - Analgin.

Lytic injections

A fever remedy for children (the composition and proportions of the antipyretic mixture depend on the general condition of the child) may contain from 2 to 3 different drugs that enhance each other’s therapeutic properties.

Analgin with Diphenhydramine

The dose and composition of the lytic mixture based on the injection solution of Analgin and Diphenhydramine are determined individually depending on the age and body weight of the child. For children under 12 months of age, it is necessary to use 0.1 ml of Analgin with a concentration of the active substance of 50%. This drug is mixed with 0.5 ml of 1% Diphenhydramine solution.

These medications are drawn into a syringe one by one, mixed in it, and then injected into the gluteal muscle. For a child over 12 months. The dosage of the lytic mixture is calculated by multiplying 0.1 ml of Analgin by the number of full years of the patient. The dose of Diphenhydramine solution is increased to 1 ml without performing any mathematical calculations.

Troychatka – Analgin, Diphenhydramine, Papaverine

The preparation of the triad is carried out following the same steps. The dosage of injectable Analgin and Diphenhydramine remains unchanged. A solution of Papaverine hydrochloride with a concentration of 2% is added to these drugs.

For children under 1 year of age, the dose of this medication is 0.1 ml. A child over 12 months of age is advised to use a dosage of 0.2 ml of this antispasmodic solution.

All components of the triad are mixed in the cavity of a sterile disposable syringe. The lytic injection is given into the upper part of the gluteal muscle. For children under 1 year of age, an injection of an antipyretic drug may be given into the muscle tissue of the outer thigh.

Analgin, Paracetamol, Suprastin (Tavegil, Fenistil)

With the advent of safer and more potent drugs of a new generation, the therapeutic composition of the lytic mixture has been updated.

In this regard, Paracetamol and the antihistamine Suprastin can be included in the antipyretic complex. In this case, a combined version of the lytic is used. Analgin solution 50% concentration is prescribed in the dosage described in the sections above.

Paracetamol is taken 1 tablet, and Suprastin is administered intramuscularly 1 ml at a time. Before mixing injection solutions, you must take 1 tablet of Paracetamol. Then draw the required amount of Analgin into a sterile syringe, calculating the dosage in accordance with the age of the child, and then add Suprastin to it.

Analgin, Diphenhydramine, No-spa

Lytichka for fever for children (the composition and proportions of the antipyretic drug vary depending on the severity of the symptoms) is a mixture of medications that may include Analgin, Diphenhydramine and No-shpa.

The first 2 components are mixed in the standard dosage, which is indicated in the previous sections. Add 1 ml of No-shpa to a syringe with a solution of Analgin and Diphenhydramine. All components of the preparation are thoroughly mixed and then injected into the upper part of the gluteal muscle.

How to prepare the mixture

To create a lytic mixture, all its components are combined together. It is then distributed intramuscularly (in the form of injections) or orally (in the form of tablets).

For injection

When preparing a lytic mixture for injections, the following is injected into the syringe:

1. 2 ml analgin.
2. 2 ml papaverine.
3. 1 ml diphenhydramine.

The sequence of drugs taken does not change.

If it is incorrect, the following happens:

• weakening of the immune system;
• loss of sensitivity to antipyretic drugs;
• harm to the body.

For oral administration

The tableted version of the lytic mixture is better than the injectable one, since after the onset of an allergy it is always possible to do a gastric lavage. The solid form of the combination medicine for high fever is made from the same drugs that are included in the liquid one. Tablets (1 piece each) are crushed or drunk whole. Their effect appears only after 30-60 minutes.

Lithium from tablets

The lytic mixture can be used to quickly reduce body temperature that is too high, not only in the form of intramuscular injections, but also in tablet form. This method of symptomatic therapy is used if there are contraindications to the injection of lytic.

Analgin, Paracetamol, Suprastin

To quickly reduce high body temperature, eliminate signs of chills and fever, you need to take 1 tablet of Analgin, Paracetamol and Suprastin. These medications should be taken with plenty of water. On average, at least 200-250 ml of liquid should enter the stomach.

This is necessary in order to eliminate the factor of irritation of the mucous membrane of the stomach and intestines. In general, these medications are taken with or after meals. Due to the painful state of the body and lack of appetite due to high body temperature, you can limit yourself to drinking plenty of fluids.

Analgin, Paracetamol, No-spa

A lytic mixture based on Analgin, Paracetamol and No-shpa allows not only to normalize the child’s body temperature, but also has an antispasmodic effect, dilates blood vessels, and facilitates breathing.

The last property of this composition is especially important in acute tracheitis or laryngitis, when the patient has a fever, swelling of the laryngeal mucosa, and a dry barking cough.

To relieve these symptoms, the child must be given 1 tablet of each of the above drugs. In this case, you should record the time you take the medications, since the lytic mixture in tablet form should also be taken at an interval of 6 hours.

Baralgin, Papaverine, Suprastin

The lytic complex of drugs in the form of Baralgin, Papaverine and Suprastin allows you to achieve antipyretic, analgesic, anti-inflammatory and decongestant effects. These drugs are taken simultaneously without following a special order of administration, but with the consumption of a large amount of liquid (at least 250 ml).

Contraindications to papaverine in litichka for fever for children

In order to quickly relieve pathological symptoms, it is necessary to use 0.5 tablets of Baralgin, as well as 1 tablet of Papaverine and Suprastin. After taking medications, the child should be provided with complete rest.

The therapeutic effect occurs after 15-20 minutes. with gradual normalization of general body temperature, elimination of headaches, redness of the skin.

Lytic mixture for children - dosage in tablets

If a baby begins to go hysterical at the sight of a syringe and needle, you should not test the strength of his nervous system. This drug can be given in tablets. An individual calculation is also required so that the dose of the lytic mixture for children ultimately turns out to be strong, sufficient to begin a rapid recovery. You need to mix a quarter of a tablet of Analgin, No-shpa, Suprastin, and take the prepared antipyretic orally with water. Otherwise, you can damage the gastric mucosa and slow down the process of absorption of components into the blood.

Lytic mixture application table

In order to exclude the factor of overdose, as well as to take the lytic mixture in a timely manner in conditions of long-term persistence of high body temperature, you should follow the schedule for the use of antipyretics.

This schedule for the use of the lytic mixture is designed for a patient with a severe infectious-inflammatory process, when high body temperatures remain throughout the day and night.

If after 1 injection of lytica there is no further appearance of fever, then repeated administration of medications is not required. The child should receive symptomatic therapy, but with a mandatory 6-hour interval between the use of drugs.

Indications for taking the lytic mixture

A pediatrician can prescribe a lytic mixture to a child who exhibits the following symptoms:

• a significant increase in temperature, the value of which is above 38, and is accompanied by pallor;
• convulsive condition developed due to high temperature;
• lack of results after taking previously prescribed medications;
• progression of deterioration of the child’s condition;

If a child develops seizures, doctors strongly recommend calling emergency help immediately, since further development of complications can lead to irreversible consequences.

Side effects and contraindications

A fever remedy for children (the composition and proportions of medications must be determined by the attending physician) is contraindicated for use in the following cases:

• allergic reaction to one of the components of the mixture;
• there are sharp or aching pains in the abdomen;
• less than 6 hours have passed since the previous dose of Lytica;
• the child's age is less than 6 months;
• hemolytic anemia;
• renal or liver failure;
• concomitant pathologies associated with inhibition of the hematopoietic process.

The lytic mixture is well tolerated by patients of all age groups. Especially if it contains the antihistamine Suprastin, which eliminates the allergic reaction factor.

At the same time, litichka has the following side properties:

• various types of allergic reactions in the form of skin rash, swelling of epithelial tissues, itching;
• leukopenia;
• bronchial spasm;

  
  First aid for symptoms of bronchospasm

• staining of urine red, which is associated with the peculiarities of Analgin’s metabolism;
• thrombocytopenia;
• disruption of the functional activity of the liver and kidneys;
• anaphylactic shock;
• headache;
• agranulocytosis.

If side effects occur, it is necessary to stop further use of the lytic mixture, and also report any symptoms to the attending physician who prescribed therapy with a complex of antipyretics.

Mixture composition

Lytic mixture for adults is a composition that is often used by ambulance specialists.

The drug includes the following components:

Despite the fact that the components are combined into one composition, they each act separately. Analgin can lower body temperature (it can be used without other components of the mixture, and it will still lower the temperature).

Diphenhydramine can increase the effect of analgin, ease breathing, eliminate a runny nose, relieve allergic manifestations of the problem and dry out the mucous membranes. However, a side effect may occur in the form of drowsiness, which helps the patient relax and get enough sleep. Papaverine can relieve pain and dilate blood vessels, allowing the body to release heat well.

The lytic mixture can only temporarily and symptomatically lower the temperature. The cause must be treated with special means. If it is a virus, an antiviral drug will do; if it is bacteria, you need to take antibiotics. Sometimes surgery is required to remove the source of inflammation, for example, the appendix, boils.

Overdose

If the rules for dosing with the lytic mixture are violated, as well as if it is taken for longer than 7 days, the following symptoms of overdose may occur:

• nausea;
• vomiting;
• loss of appetite;
• diarrhea;
• tachycardia;
• drowsiness;
• confusion;
• state of delirium;
• decreased blood pressure;
• constant feeling of cold.

Patients with signs of an overdose of Lyticum should be hospitalized in a toxicology department. Detoxification therapy involves gastric lavage, taking sorbents, and salt-based laxatives. In case of loss of consciousness and severe poisoning of the body, hemodialysis is prescribed.

Contraindications and possible side effects

This medicine should not be used if:

• the presence of individual intolerance to at least one of its components (if necessary, it is recommended to conduct a test: drop 1 drop of the drug on the lower eyelid and observe for 30 minutes the possible manifestation of allergic reactions);
• abdominal pain due to fever;
• the use of at least one of the components of the mixture in the previous 4 hours;
• less than 6 months old;
• severe diseases of the kidneys, liver and gastrointestinal tract.

The lytic mixture is not at all a harmless drug, and therefore can cause the following side effects:

• the appearance of allergic reactions;
• excessive drop in blood pressure;
• decreased urine volume (diuresis);
• drowsiness;
• nausea and vomiting;
• dry mouth;
• disorder of the gastrointestinal tract.

As already mentioned, “abuse” of this drug can reduce the sensitivity of the child’s body to other antipyretics.

Interaction with other tools

The lytic mixture is not recommended to be taken simultaneously with medications from the following pharmacological groups:

• tricyclic antidepressants - there is a toxic effect on liver tissue;
• barbiturates and medications based on phenylbutazone - weaken the effect of Analgin;
• all types of non-narcotic analgesics - the risk of developing intoxication of the child’s body increases;
• indomethacin-based products - enhances the therapeutic properties of the lytic mixture;

• tranquilizers and sedatives - prolong the analgesic effect.

While using the lytic mixture, it is recommended to refrain from simultaneously taking any medications classified as anti-inflammatory non-steroidal drugs.

For adults

What is the composition of the lytic mixture for injections for adults? Analgin, papaverine (2 ml each) and diphenhydramine (1 ml) are taken into the syringe. The set is performed exactly in this sequence. If you inject yourself, you can inject it on the front of the thigh, inserting the needle 4 cm.

The composition and dosage of the lytic injection for adults has some differences from the children's version, but the product still works just as effectively. If a fever appears after some time, the injection should not be repeated; you must call an ambulance or find a way to get advice and help from a doctor.

Storage

The injection solution of the lytic mixture should be used immediately after its preparation by mixing the constituent medications.

The preparations on which the litichka is prepared are stored at an air temperature not exceeding +25 degrees Celsius in the manufacturer’s original packaging. The shelf life of analgesic and antipyretic drugs does not exceed 3 years, after which further use of medications is prohibited.

Lytichka for fever is a complex of antipyretic, analgesic, vasodilator and anti-inflammatory drugs that can quickly normalize the body's heat exchange and relieve painful symptoms caused by the inflammatory process.

The lytic mixture is indicated for use in children of all age groups, with the exception of patients under 6 months of age. The composition and proportions of the lytic are determined by the attending physician depending on the child’s condition. The duration of therapy with antipyretics should not exceed 5 days.

How long does it take for the lytic mixture to work?

Having studied the indications for use, it is clear that the effect of the powder is weaker. Therefore, it is better to perform injections. After taking the tablets, the temperature stabilizes after 25-30 minutes. The increase resumes after a couple of hours. If you give injections for the flu, the effect of a single dose begins 10 minutes after the injection. The therapeutic effect lasts for 3-4 hours, then the symptoms and sensations recur. Therefore, another injection is required. This is how long the lytic mixture works for children, but these are relative indications - it all depends on the nature of the disease.